Brain fog and mental fatigue are among the most frustrating menopause symptoms. On The Tamsen Show, Dr. Mindy Pelz talks about fasting as a way to support brain energy, not as a rigid or punishing approach.
She explains that as estrogen declines, the brain may become less efficient at using glucose for fuel. Ketones, which are produced when the body burns fat, can offer an alternative energy source. According to Dr. Pelz, intermittent fasting can help the body access ketones more regularly.
She recommends starting gently. A fasting window of about 13 to 15 hours works well for many women, with flexibility depending on stress levels, sleep, and life demands. She also notes that women who are still cycling may need to avoid fasting in the days leading up to their period.
Dr. Pelz discusses longer fasts as an optional tool for some women, explaining that extended fasting increases ketone production and activates cellular repair processes like autophagy. She emphasizes preparation, gradual experimentation, and medical guidance when exploring longer fasts.
Research supports that fasting can activate autophagy and that ketones may offer neuroprotective benefits (de Cabo & Mattson, New England Journal of Medicine, 2019).
Dr. Pelz’s core message is simple: fasting should feel supportive, not stressful. The goal is clarity, resilience, and energy, especially during midlife transition.
If you want to learn more, listen to this episode of The Tamsen Show.















