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What Is Vaginal Estrogen and Why It’s a Game-Changer in Midlife | The Tamsen Show

October 23, 2025

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What Is Vaginal Estrogen and Why It’s a Game-Changer in Midlife | The Tamsen Show

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If you’ve been told that recurring UTIs are just part of getting older, it’s time to rethink that.

According to Dr. Mary Claire Haver on The Tamsen Show, “The number-one treatment for recurrent UTIs in women is vaginal estrogen not recurrent antibiotics.”

Vaginal estrogen is a localized, low-dose form of hormone therapy that restores tissue health inside the vagina and around the urethra. Unlike systemic HRT, it doesn’t enter the bloodstream and doesn’t affect breast or bone tissue (see NAMS 2023 Position Statement on Genitourinary Syndrome of Menopause).

The treatment helps rebuild the thin, dry tissue that develops as estrogen levels drop in midlife reducing infections, discomfort, and painful intimacy.

Studies show that vaginal estrogen can cut UTI rates by up to 50 percent (Paavonen et al., Climacteric, 2019). It’s considered safe even for many women with a history of hormone-sensitive breast cancer when supervised by their oncology team (Obstetrics & Gynecology, 2020).

Dr. Haver stresses this isn’t a “luxury” treatment, it’s preventive care that protects vaginal and urinary health well into post-menopause.

For the full conversation, listen to this episode of The Tamsen Show

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