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From low libido to painful sex to the truth about testosterone, Dr. Kelly Casperson is back, and this time, she’s answering your questions.
In this episode, Tamsen sits down with Dr. Casperson, the leading urologist, author, and leading voice in women’s sexual health for an honest, no-shame conversation about what’s really happening to women’s bodies in midlife. She explains how hormones shift during perimenopause and menopause, why desire changes, and what women can actually do to feel better in their bodies again.
From hormone therapy and vaginal estrogen to confidence, pleasure, and how to start these conversations with your doctor (or your partner). It’s real answers, real science, and the kind of clarity every woman deserves.
Here’s what you’ll learn:
- What’s really happening to your hormones during perimenopause and menopause
- Why libido and energy change and how to get them back
- The truth about testosterone for women
- How hormone therapy really works and when to consider it
- The connection between vaginal health, confidence, and pleasure
It’s everything you’ve been wondering about your body, finally explained, with truth, humor, and heart.
Watch the Full Episode Here: https://www.youtube.com/@TamsenFadalTV
Get my new book, How To Menopause, Take Charge of Your Health, Reclaim Your Life and Feel Even Better Than Before 💖 https://www.tamsenfadal.com/how-to-menopause
00:00 Intro
06:10 What Estrogen and Testosterone Actually Do for Your Sex Drive
09:21 Why “Menopause Is Natural” Can Be Misleading
11:01 GSM Explained: Painful Sex, UTIs, and the Fix Nobody Mentions
13:35 The Truth About Spontaneous vs. Responsive Desire
18:40 Vaginal Estrogen: What It Is, How It Helps, Why It’s Safe
22:31 Best Lubes for Women 40+ (And What to Avoid)
27:43 Sharp Pain During Sex Is Not Normal
32:16 Testosterone for Women: Why We Deserve FDA Approval
38:48 Are Testosterone Pellets Safe? What You Should Know
45:56 How to Rekindle Desire in Long-Term Relationships
52:08 BONUS: Why Your Hair Is Thinning in Perimenopause
57:05 Hair Health Is Hormone Health And What to Watch For
You can find Dr. Casperson:
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Visit her website
Get Dr. Casperson’s new book, The Menopause Moment.
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Medical Disclaimer:
The information provided in this podcast is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional regarding any medical concerns or treatment options. The views expressed by guests are their own and do not necessarily reflect those of The Tamsen Show.
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I’m an Emmy Award-winning journalist, filmmaker, author, speaker, certified integrative nutrition coach, and passionate menopause advocate.

New Episodes Drop Every Wednesday!
Every episode of The Tamsen Show is here to help you navigate every stage of life with confidence. From career pivots to menopause, relationships to reinvention, Tamsen tackles the conversations women actually need, with real talk from experts, wellness advice and no filters.

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